Pharma Focus Asia

Aro Collaboration with Ionis Advances with Option Exercise

Wednesday, October 07, 2020

Aro Biotherapeutics, a biotechnology company focused on developing a new generation of medicines based on its proprietary CENTYRIN™ technology, announced today that Ionis Pharmaceuticals, Inc., the leader in RNA-targeted therapeutics, has exercised an option to acquire a license to an undisclosed antisense oligonucleotide (ASO)-Centyrin drug conjugate. In December 2019, Aro and Ionis entered into a licensing and collaboration agreement to advance a defined number of ASO-Centyrin drug conjugates. Ionis is leveraging Aro’s CENTYRIN technology to enhance the activity of ASOs via tissue-specific delivery, resulting in more efficient inhibition of disease-causing RNAs and proteins.

“We remain excited about the promise of our combined technologies to bring new treatment options to patients,” said Susan Dillon, Ph.D., Co-Founder and Chief Executive Officer of Aro Biotherapeutics. “Ionis’ work in RNA-targeted therapeutics is transformative and we look forward to the continued advancement of new ASO-Centyrin therapeutic candidates as part of our collaboration.”

“Leveraging Aro Biotherapeutics’ unique CENTYRIN technology to develop drug candidates with targeted cell- and tissue-specific delivery of our novel antisense medicines will help further expand Ionis’ already robust pipeline, allowing us to say “yes” to even more patients who depend on Ionis for transformative therapies,“ said Frank Bennett, Ph.D., Ionis’ Chief Scientific Officer.

magazine-slider-imageMFA + MMA 2024CPHI Chine || PMEC China 2024Asia Healthcare Week 2024Advance DoE WorkshopNitrosamine Advance Workshop 2024CPHI Korea 2024CHEMICAL INDONESIA 2024INALAB 2024 Thermo Scientific - DynaDrive and DynaSpinDigital Health Asia 2024Rehab Expo 2024ISPE Singapore Affiliate Conference & Exhibition 20242024 PDA Pharmaceutical Manufacturing & Quality Conference2024 PDA Cell and Gene Pharmaceutical Products Conference 2024 PDA Aseptic Manufacturing Excellence Conference2024 PDA Aseptic Processing of Biopharmaceuticals ConferencePharma Quality Excellence Awards 20244th Annual Pharma GMP Quality Management 20243rd World ADC Asia 2024LogiPharma Asia 2024