Pharma Focus Asia
KP - Choose our fully recyclable blister films

Otsuka Pharmaceutical Collaborates with ShapeTX

Friday, September 08, 2023

Otsuka Pharmaceutical and ShapeTX have announced a significant collaboration to develop intravitreally-delivered adeno-associated viruses (AAVs) for the treatment of ocular diseases, with the option to expand the scope of their work to include additional targets and tissue types. 

This collaboration brings together ShapeTX's AAVidTM capsid discovery platform and transgene engineering technology with Otsuka's expertise in genetic payload design and ophthalmology to create innovative therapies for individuals affected by serious eye conditions.

According to the terms of the agreement, ShapeTX will receive an initial payment from Otsuka and stands to receive further payments tied to development, regulatory milestones, and sales achievements, with the total potential value of these payments exceeding $1.5 billion. Additionally, ShapeTX will be entitled to receive tiered royalties on the sales of any products resulting from this collaborative effort.

The primary objective of this collaboration with ShapeTX is to enable the delivery of vectorised antibody drugs alongside AAV technology. This approach is designed to specifically target disease-related cell types within the eye and offer a one-time, curative treatment with sustained lifetime expression.

Latest Issue
Get instant
access to our latest e-book
THERMOFISHER SEACertara - Is your drug program on trackMasterControl - Manufacturing demoMasterControl - QMS demoBora Pharmaceuticals - Free WhitepaperThermo Fisher Scientific - Rapid Mycoplasma TestingThermoFisher Scientific - Save costs on your downstream process todayThermo Fisher Scientific - PeptonesMerck - Mobius® products5th Annual Pharma Manufacturing and Automation Convention 2023DUPHAT 202410TH ANNUAL GCC PHARMACY CONGRESS 2023Reuters Events - Pharma Customer Engagement USA 202314th Annual Emirates Cardiac Society Conference 2023The International Hand & Wrist Congress 2023LabAsia 2023Pharma & Patient USA 2023Pharma Customer Engagement Europe 2023
MasterControl - 6 Essential Features in an eQMS