Pharma Focus Asia

SRI International Announces Drug Research Collaboration with Ionis Pharmaceuticals

Wednesday, July 11, 2018

SRI International today announced a research agreement with Ionis Pharmaceuticals, combining SRI's proprietary FOX Three Molecular Guidance cellular targeting system (MGS) with Ionis' proprietary antisense drug-discovery platform.

SRI's FOX Three MGS technology is designed to overcome cellular barriers that prevent intracellular delivery of large-molecule biotherapeutics. The platform uses proprietary technology that enables the delivery of macromolecular payloads to select cells and subcellular locations in those cells.

SRI has demonstrated that the FOX Three MGS technology can deliver more than a dozen different types of payloads - from functional enzymes, antibodies and DNA, to liposomes and nanoparticles - to targeted, intracellular molecular-target locations previously considered undruggable.

"Fox Three creates the potential to greatly expand the use of biotherapeutics," said Nathan Collins, Ph.D., vice president of SRI Biosciences, a division of SRI International. "Ionis is an ideal partner to further explore the utility of this technology in the intracellular delivery of nucleic acid-based drugs. We look forward to seeing what we can accomplish through thoughtful combination of our novel technologies."

magazine-slider-imageMFA + MMA 2024CPHI Chine || PMEC China 2024Asia Healthcare Week 2024Advance DoE WorkshopNitrosamine Advance Workshop 2024CPHI Korea 2024CHEMICAL INDONESIA 2024INALAB 2024 Thermo Scientific - DynaDrive and DynaSpinDigital Health Asia 2024Rehab Expo 2024ISPE Singapore Affiliate Conference & Exhibition 20242024 PDA Pharmaceutical Manufacturing & Quality Conference2024 PDA Cell and Gene Pharmaceutical Products Conference 2024 PDA Aseptic Manufacturing Excellence Conference2024 PDA Aseptic Processing of Biopharmaceuticals ConferencePharma Quality Excellence Awards 20244th Annual Pharma GMP Quality Management 20243rd World ADC Asia 2024LogiPharma Asia 2024