CleanCap technology is the fastest and easiest way to produce a 5’ Cap 1 mRNA structure with 95% efficiency. The “one‑pot” solution requires fewer steps and less equipment than enzymatic capping—allowing for a quicker process, greater production potential, and a better return.
As a revolutionary solution to mRNA capping for vaccine and therapeutic production, CleanCap technology offers many advantages over traditional enzymatic capping:
GMP Grade Available
3x Transcriptional Yield
One-Pot Synthesis for Superior Efficiency
Reduces Immunogenicity
Natural Cap 1 Structure
From research use to GMP grade, CleanCap technology is available in a variety of formats to meet your unique production needs:
GMP Custom mRNA Manufacturing
Custom mRNA Manufacturing
Capping Reagent—Research and GMP Grades
Stocked mRNA with CleanCap Reagent AG
Natural Cap 1 Structure
