Pharma Articles

Articles on key issues related to the pharma industry from the heads of leading pharmaceutical companies and pharma industry experts across the globe. The pharma industry articles' section focuses on current and emerging issues in areas such as Strategic developments in the pharma industry, pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical manufacturing, biopharmaceuticals, and information technology.

Mussel-inspired Bio-adhesives

Enhancing Topical Drug Delivery For Dermatological Applications
Musselinspired bioadhesive gels utilising catecholcontaining compounds provide strongand reversible adhesion to the skin They enhance drug retention enabling sustained releasefor applications in wound healing scar management and targeted transdermal drug delivery in dermatology

Therapeutic Peptides

Medicine's new frontier for targeted treatment
Therapeutic peptides are a promising frontier in precise medicine leveraging unique properties for targeted treatment Advancements in production modification and delivery have surmounted challenges Originating from human hormones and natural sources peptides hold potential for various conditions inc...

Demystifying Lead-time bias and Length-time bias in Clinical Trials

The use of timetoevent analysis is common in clinical research The interpretation of timetoevent analysis can often be misleading Beginners and early career researchers struggle to grasp the concepts and nuances in a timetoevent analysis

Determinants of Antimicrobial Resistance (AMR) Research in South East Asia

In the year Alexander Fleming made an outstanding medical history by discovering penicillin which helped to combat numerous deadly infections which previously had serious consequences upon human lives

The Emergence of Organ-on-chips for Diseases Studies and Drug Development

In recent years Organonchips OOC attracted large interest as a new enabling technology to better understand human pathophysiological mechanisms and develop new drug treatments

Design of Self-antibacterial and Biocompatible Titanium Surfaces for Biomedical Applications

Metals and alloys are the first generation bioinert biomaterials These materials possess excellent mechanical strength low elastic modulus and good corrosion resistance Titanium Ti and its alloys are one of the commonly used metallic biomaterials for orthopedic applications eg bone plates screws den...

The Past, Present, and Future of Sickle-cell Disease Registries: Findings from a Global Review

Patient registries are important tools in the healthcare system for systematically collecting data over time from a population living with a certain disease condition or exposure Welldesigned and wellexecuted patient registries hold great potential in providing important disease insights into for e...

Lipid Excipients and Formulation Development

An overview
The successful introduction of commercial lipidic formulations of cyclosporine as Sandimmune in followed by its reformulation as Neoral has raised interest of the lipidbased drug delivery technology over the past two decades With a greater understanding of the various functions lipids may have in b...

Smart Polymeric Nanocomposites for Cancer Therapeutics

Globally cancer is the second most prevalent healthcare issue following cardiovascular Conventional methods such as chemotherapy and radiotherapy have several detrimental side effects without guaranteed permanent recovery In the last few decades efforts have been made by introducing nanotechnology t...

Repurposed Drugs against the Latest Variants of Concerns of SARS-CoV-2

The severe acute respiratory syndrome coronavirus SARSCoV affected all areas of life and the economy by causing COVID and created alarming caution in the form of variants of concerns VoC The latest VoC that are of public health relevance are Alpha B Beta B Gamma P Delta B and Omicron B Due to the em...

Role of Nutraceutical in Various Diseases - A Review

DeFelice introduced the term nutraceutical in combining the words nutrition and pharmacy and originally defined it as a food or part of a food that provides medical or health benefits including the prevention and treatment of disease A nutraceutical may be a nutrientdense food like spirulina garlic...

5 Proven Ways to Take PBM’s to the Future ‘Today’ with Conversational AI

Gone are those if youre still thinking of keeping your customers engaged with your brand by merely sending emails messages phone calls or mobile apps They are expecting way beyond that today It begs the question Is the rapid evolution of selfservice tools creating the need to expect more and more

Effect of Size of Protein Therapeutics on Brain Pharmacokinetics following Systemic Administration

Many antibodybased therapeutics have been developed to treat the CNS disorders Howeverhow to achieve a sufficient exposure of protein therapeutics in the CNS is the major challenge in drug development The bloodbrain barrier BBB and the bloodcerebrospinalfluid barrier BCSFB highly regulate and limit...

Industry 4.0 at Bachem

Innovation and operational excellence are two important pillars of Bachems success Thus to keep technological leadership and highquality services it was essential to start our digital transformation and to enter the Industry area This will benefit our customers as we will be able to increase our ca...

Alpha-fetoprotein as a Shuttle for Medicines

Pregnancy is a natural phenomenon that ensures the survival of the species The suppression of the immune response in pregnancy is robust since the embryo cells have half the fathers proteins that should be recognised by the mothers immune system as foreign Even surrogate motherhood is possible with...