Charles River and Insightec Partner to Advance Neuroscience Therapies with Focused Ultrasound
Thursday, September 05, 2024
Charles River Laboratories International and Insightec have announced a five-year strategic collaboration. This partnership will provide Charles River's clients access to a global platform for the use of focused ultrasound (FUS) in drug discovery and preclinical development, particularly within neuroscience.
The collaboration is aimed at advancing the development of genetic medicines, biologics, and immunotherapies in various preclinical neuroscience models, following Good Laboratory Practice (GLP) standards.
Charles River collaboration with Insightec marks a key development in neuroscience research. The future of drug discovery, technology will play a vital role in driving innovation. Integrating focused ultrasound into our preclinical services will enhance the precision of drug delivery, refine research models, and support the discovery of new therapies.
Insightec's low-frequency ultrasound technology offers a non-invasive method of disrupting the blood-brain barrier, enabling targeted drug delivery to specific brain areas. The technique has shown positive clinical results in treating various neurological conditions, including Parkinson's and Alzheimer's diseases, as well as certain oncology cases.
This approach holds significant potential for improving the effectiveness of neurological treatments and patient outcomes.
Insightec's focused ultrasound technology, combined with microbubble resonators, allows for precise drug delivery to deep brain structures, which could transform treatment for challenging central nervous system (CNS) conditions. These include neurodegenerative, neurodevelopmental, and neuro-oncological diseases.
Insightec commented this partnership will not only extend the use of our low-frequency ultrasound technology but also accelerate the development of innovative therapies for neurological disorders.
By combining Insightec's expertise aims to transform the way new treatments are delivered to the brain, improving the lives of millions around the world.
Source: prnewswire.com