Manufacturing
Modelling and its Applications in Solids-based Continuous Pharmaceutical Manufacturing Processes
In recent years the pharmaceutical industry has been actively involved in exploring advanced manufacturing processes that can help reduce the manufacturing costs and improve the product quality One of the most promising route is the switch from batch to Continuous Pharmaceutical Manufacturing CPM processes The continuous production mode enables a s...
Safe and Secure
Packaging\\\'s role in combating counterfeit drugs
According to data released by the United States Food and Drug Administration USFDA approximately per cent of all pharmaceuticals sold globally are counterfeit Whilst counterfeiters are active around the world not all markets suffer equally Unsurprisingly the World Health Organization WHO reports that developed nations such Europe and the USA are...
The Rise in Sterile Manufacturing
A focus on containment
Containment is key during aseptic processing and this has led to the development of new transfer methods that are both enclosed and minimise the requirement for operator intervention In this article Christian Dunne global product manager of AseptiSafe at ChargePoint Technology discusses modern containment methods and the advent of split butterfly v...
Cultural Excellence as the Foundation
For effectiveness of the quality system
In pharmaceutical companies it is universally understood that a robust Pharmaceutical Quality System PQS provides key elements of assurance and oversight for pharmaceutical manufacturing and quality control laboratory processes It ensures that patients are provided with medications that are safe effective and reliably produced at a high level of qu...
A Hard Pill to Swallow
Measuring texture in novel oral dosage forms
Oral drug delivery is one of the most convenient and most common methods of delivering medication Its simplicity and costeffectiveness have made it particularly popular with manufacturers in the pharmaceutical industry but it is not always the most popular with consumers The trouble with tablets Traditionally orallyadministered drugs are disp...
Real-Time in- Line Monitoring
For high shear wet granulation
High Shear Wet Granulation HSWG a critical step in many applications in the pharmaceutical industry transforms fine powder blends into more freeflowing granules optimised for solid dosage form production Manufacturers rely extensively RealTime inLine Monitoring For high shear wet granulation on granulation as it can enhance blend uniformity minimis...
A Novel Continuous Pharmaceutical Manufacturing Pilot-Plant
Advanced model predictive control
Continuous Manufacturing CM is evolving into a preferred platform for pharmaceutical products involving solid dosage forms The US Food and Drug Administration FDA has recently approved some pharmaceutical products to be manufactured in continuous line with several others on the way Therefore the pharmaceutical industry is going through a paradigm s...
Added Costs for Added Protections
The impact of implementing safety features in pharmaceutical packaging and labelling
The global pharmaceutical market is a complex and dynamic industry that is continuously evolving in response to a variety of market influencers The landscape of the pharmaceutical market has changed significantly with the rise of generic drugs and the rapid expansion of mergers and acquisitions Many companies are reevaluating the location of their...
Continuous Manufacturing
Are we there yet?
In US FDA issued guidance document PAT A Framework for Innovative Pharmaceutical Development Manufacturing and Quality Assurance To encourage the pharmaceutical industry to adopt novel manufacturing methods it cited industry resistance as follows the pharmaceutical industry generally has been hesitant to introduce innovative systems into the manu...
Pharmaceuticals are in Good Hands with Turkish Cargo
As Turkish Cargo we have been awarded with IATAs Center of Excellence for Independent Validators CEIV in Pharmaceutical Logistics at our Istanbul hub With this strength we aim to offer our customers the most reliable means of transport As an air freighter speed of delivery wide network and safety are some aspects of our efficiency When it comes to...
