Manufacturing
Demand-driven Manufacturing
Designing profitable supply chain
The global pharmaceutical market has never been more competitive and therefore companies are searching for sources of sustainable value Consider the increased competition created by a flood of metoo drugs combined with everdecreasing rates of pipeline productivity and the need for the significant changes to healthcare delivery models As margins con...
Improving Pharmaceutical Manufacturing Performance
Improving Pharmaceutical Manufacturing Performance
The Pharmaceutical Research Manufacturing Project was launched in The projects goals are twofold first to investigate the likelihood and type of enforcement efforts utilised by the US FDA and second to investigate the effects of managerial technical and organisational practices on pharmaceutical manufacturing and deviation management performance B...
Redesigning Drugs to Enhance Performance
Programs to identify and evaluate novel therapeutic agents are expensive take a long time and do not guarantee a successful outcome Proving safety and efficacy is difficult complex and slow Furthermore even after efficacy and safety are demonstrated and the compound becomes a medicinal product the complexities of disease and of the drug action alli...
Continuous Process Performance Monitoring Using Nelson Rules
Regulatory agencies expect that there should be a system for process monitoring for detecting unplanned departures from the process during manufacture and to identify future process improvement opportunities in order to provide continual assurance that the process is in a state of control validated state during manufacture to ensure desired product...
Supply Chain Design
An outside-in perspective
The global pharmaceutical market has never been more competitive and therefore companies are searching for sources of sustainable value Consider the increased competition created by a flood of metoo drugs combined with everdecreasing rates of pipeline productivity and the need for the significant changes to healthcare delivery models As margins con...
Drugs, Lies and Regulations
In July counterfeit Lipitorr was discovered in the legitimate UK supply chain It is the latest instance of counterfeit medicines found and further evidence that counterfeiters and criminals appear to be targeting the legitimate pharmaceutical market This type of activity can undermine the integrity of the medicines supply chain and can damage pati...
Recent Advances in Analytical Methodologies for the Determination of Impurities in Drugs
Safety and efficacy of pharmaceuticals are two fundamental issues of importance in drug therapy The safety of a drug is determined by its pharmacologicaltoxicological profile as well as the adverse effects caused by the impurities The impurities in drugs often possess unwanted pharmacologicaltoxicological effects by which any benefit from their adm...
Pharmaceutical Manufacturing in Singapore
Singapore is a thriving pharma location with a proven track record for pharmaceutical manufacturing Companies with significant operations in Singapore include GlaxoSmithKline GSK Merck Novartis Pfizer SanofiAventis ScheringPlough Wyeth and Kaneka Maintained Growth Momentum At the launch of Singapores Biomedical Sciences BMS initiative in
Flexible BioPharmaceutical Production Solutions
As with all technologies today the advancements within the life sciences industry are accelerating beyond what any of us have experienced in the past Every facet of our industry from early drug discovery and development through human trials and commercial manufacturing are evolving at a rate that was unthinkable a decade ago What was considered cut...
Meeting Singapore\\\'s Chemical Needs
The Institute of Chemical and Engineering Sciences ICES is one of the research institutes under the Agency for Science Technology and Research ASTAR Established in the mission is to develop scientific knowledge RD manpower and technological capabilities to support current and future needs of Singapores chemical biomedical and process engineering i...
