Research & Development

COMPUTER AIDED DRUG DESIGN IN PHARMA R&D

The number of new US FDA approved drugs is declining in spite of lots advances made in science

PRECISION MEDICINE

MATCHING BIOSPECIMENS BECOMES A MORE EXACT SCIENCE

For many drug discovery programmes HBS form the foundation of many hypotheses and contribute to research that is the basis for gonogo decisions during the development process

Apoferritin as a Nanocarrier

Its applications in medicine

In the recent years Research Development RD in the area of nanoscience and nanotechnology has increased rapidly

Academic Ventures and Professional Service Companies

Partnering issues in early stage drug development

Over the past few decades life science and pharma have been characterised by a series of radical changes that have been at the origin of an impressive transformation of RD processes and have made them a favoured scenario for radical change in the innovation paradigm

MICRONEEDLE ARRAY PATCHES

The way forward for the management of diabetes

Diabetes Mellitus DM is a chronic lifethreatening disease just like cancer or any other disease whose incidence has become doubled in recent years In diabeties patients the use of intensive insulin therapy was found to reduce long term vascular complications and some evidence also highlights the increased risk of both hyperglycemia and hypoglycemia...

ADVANCED MODELLING AND SIMULATION

Helps prepare medical countermeasures and optimise response to public health emergencies

What are MCMs MCMs are regulated products that can be used in a public health emergency The emergency could be due to a terrorist attack with Chemical Biological Radiological Or Nuclear CBRN material a naturallyoccurring emerging disease or a natural disaster MCMs can be used to prevent diagnose or treat conditions resulting from those natural o...

New and Novel Drug Delivery Technologies

Enhancing product lifecycle

In the recent decades most of the pharmaceutical companies often look for extensions for their patented product to enhance the products life cycle by means of various approaches like a Drug repurposing ie new indication of existing drug b Using different formulation ie by means of using new and novel drug delivery technologies and c Use of new comb...

Pre-Clinical Assessment of Drug-Induced Hypersensitivity Reactions

Tools and challenges

Drug Hypersensitivity Reactions DHRs belong to type B adverse drug reactions defined by the World Health Organisation WHO as doseindependent unpredictable noxious and unintended response to a drug at dose normally used in humans They include drug intolerance drug idiosyncrasy drug allergy and nonallergic anaphylactic reaction Most of type B reactio...

PRODUCT DESIGN & DELIVERY

By definition biology is the natural science while biotechnology utilises biological systems and living organisms to develop different products A product could be an article or substance or technology that is manufactured or refined or developed for sale for sure The list of biotechnological products broadly includes medicines medical devices diagn...

The Future of Pharma R&D

How external innovation changes pharma R&D

RD has traditionally been and will continue to be probably even more crucial for the growth and future success of researchbased pharma companies Given the industries traditional RD strategy that was built on internal innovation and the rising regulatory hurdles pharma companies continuously increased their financial input into RD related work with...