Research & Development
Research and Development of Medical Countermeasures in Asia for Pandemic and Bioterror Threats
Beginning in the mids incidents involving easily we aponised and accessible agents such as anthrax a commonly occurring bacterium and sarin a chemical toxin from a commonly used family of pesticides demonstrated the growing threat of Chemical Biological Radiological and Nuclear CBRN agents as weapons for bioterror attacks At the same time there was...
Biologics and Biosimilars
Promising field for medicines for the future
Up until a few years ago the field of medicine was largely dominated by small molecules or pharmaceuticals as they are more commonly known Large molecules or biologics were relatively less heard of and there were very few players operating globally in this area Over the past two decades the biotechnology industry has come a long way According to a...
Wearable Large Volume Drug Delivery Devices
Hold key to pharmaceutical lifecycle management, patient preference
It costs approximately US billion yuan to bring a single new drug to marketand the cost as well as the hurdles to innovation are getting higher Yet innovation is crucial to the pharmaceutical industry and the need for a strong product pipeline is sending companies racing to develop some of the most promising new treatmentsbiologicsin the hope of d...
Drug Development
A question-based process
With over two decades of experience within the realm of Drug Development behind you what are the milestones of your career journey that you would like to share with us Last two decades was really wonderful and exciting journey working in drug development industry Though I cannot claim but have experienced almost entire process of drug developme...
Redesigning Drugs
For better performance
Programs to identify and evaluate novel therapeutic agents are expensive take a long time and do not guarantee a successful outcome Proving safety and efficacy is difficult complex and slow Furthermore even after efficacy and safety are demonstrated and the compound becomes a medicinal product the complexities of disease and of the drug action alli...
Future Trends in Ion Channel and Solute Transporter Drug Discovery
Ion channels have been excellent drug discovery targets for decades with clinically meaningful drugs identified targeting sodium channels including eg lamotrigine calcium channels eg amlopdipine GABA receptors eg diazepam and ATPgated potassium channels eg glipizide and several others However new ion channel modulators have not been emerging at a r...
Enabling the Delivery of Poorly Soluble Drugs via Drug-Polymer Solid Dispersions
Poorly soluble new drugs entering the market are estimated to range from to per cent of the total This trend of increased poorly soluble drugs on the market is a result of the quest for drugs with increased potency and increased ability to interact with protein receptors The advent of modern drug discovery techniques such as quantitative structur...
Unconventional Micro and Nanofabrication
Discovering and developing a new drug is a costly and timeconsuming process Recent reports suggest that it costs around US million pretax to bring a new drug to market One approach to improve the efficiency and lower the cost of this process is to use appropriate models and assays early in the discovery phase to identify candidates that are likely...
Nanobiomechanics and Human Diseases
Insights into the pathophysiology
Human diseases not only impair bodily structures and functions but they also threaten the health and wellbeing of humans Current research on diseases focusses mainly on the microbiological immunological and pathological aspects rather than on the biomechanics of the diseases which may have direct link to their pathophysiological outcomes In fact so...
Rethinking Drug Discovery
Drug discovery is a tough business At the same time it is the domain that provides an opportunity to improve the quality of human health and allows recovering from the suffering due to various biological disorders In the past decades we have witnessed a major limitation in creating the nextgeneration drugs despite a significant boost in the fina...
