Publisher: CRC Press
Year of Publication: 2020
Author(s) : Kamal Shah,Durgesh Nandini Chauhan. Nagendra Singh Chauhan, Pradeep Mishra
Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations.