Pharma Manufacturing practices include all methods that are required to develop Pharma services. These practices provide minimum requirements that must and should be met by pharmaceutical companies in order to provide high-quality products that will pose no risk to the patients/consumers at large. Pharmaceutical contract manufacturing process involves Pharmaceutical machinery, drug manufacturers contracting a firm for finished products or components. It can be seen as a type of outsourcing. Organizations succeed by focusing on what they do best to their consumers, partners or outsourced vendors. Contract manufacturing seems to fit neatly into this scenario.

Drug Concentration Assurance of Continuous Tablet Manufacturing

Advanced process control strategy

In the pharmaceutical industry Real Time Release RTR can be facilitated by the development of a highly efficient control system The drug concentration in final tablet is one of the most critical quality attributes that must be assured before releasing the final product to the market Therefore a mult..

Pharmaceutical Crystallisation

Emerging process intensification technologies

Crystallisation is used extensively in the pharmaceutical industry for the separation and purification of chemical compounds Recently radically new technologies have been developed that allow for step improvements in the performance of pharmaceutical crystallisation This article provides a brief ove..

HPAPI Qualification Testing

Considerations in containment testing

Containment is critical in oral solid dose drug production particularly if it involves Highly Potent Active Pharmaceutical Ingredients HPAPI This article examines how containment valves and wireless monitoring can keep employees safe and improve manufacturing efficiency..

System Engineering for a Novel Continuous Pharmaceutical Manufacturing Process

Currently pharmaceutical industries are going under paradigm shift from traditional batch to novel continuous manufacturing Such a novel continuous plant has been built at CSOPS which is being adapted by several pharmaceutical companies The Continuous Pharmaceutical Manufacturing CPM pilotplant has ..

Modelling and its Applications in Solids-based Continuous Pharmaceutical Manufacturing Processes

The development of solidsbased pharmaceutical manufacturing has been facilitated by the use of process modelling and simulationbased process analysis methods Such in silico approaches are implemented to efficiently predict process behaviours identify critical process parameters and quantify the proc..

Safe and Secure

Packaging\\\'s role in combating counterfeit drugs

Counterfeiting is currently one of the biggest challenges that the pharmaceutical industry is facing and the amount of counterfeit drugs in the market globally is continuing to grow In this article Essentra explains how packaging can help to tackle the issue showing how incorporating a combination o..

The Rise in Sterile Manufacturing

A focus on containment

Containment is key during aseptic processing and this has led to the development of new transfer methods that are both enclosed and minimise the requirement for operator intervention In this article author discusses modern containment methods and the advent of split butterly valve technology to impr..

Cultural Excellence as the Foundation

For effectiveness of the quality system

In pharmaceutical companies it is universally understood that a robust Pharmaceutical Quality System PQS provides key elements of assurance and oversight for pharmaceutical manufacturing and quality control laboratory processes However despite recent advances in the manufacturing sector quality issu..

A Hard Pill to Swallow

Measuring texture in novel oral dosage forms

As the pharmaceutical industry embraces new delivery mechanisms to improve efficacy and patient compliance the author discusses how to develop novel oral dosage drugs that are robust during processing and throughout transport and storage yet easy to use safe and effective for the patient..

Real-Time in- Line Monitoring

For high shear wet granulation

This article discusses why HSWG is important and the difficulties it poses for scaleup and monitoring in the pharmaceutical industry It also introduces the fundamentals of a drag force flow technique and how that can potentially address the limitations associated with other HSWG process monitoring m..