Pharma Articles

Articles on key issues related to the pharma industry from the heads of leading pharmaceutical companies and pharma industry experts across the globe. The pharma industry articles' section focuses on current and emerging issues in areas such as Strategic developments in the pharma industry, pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical manufacturing, biopharmaceuticals, and information technology.

Identification of Vaccine Products and Drug Substances by Fourier Transform Infrared (FTIR) Spectroscopy

Vaccine manufacturing is a lengthy and complex process therefore introduction of rapid and reliable analytical methods are essential to reduce cycle time for inprocess and quality control testing In cases where confirmation of product identity is needed to make a process testing or batch disposition..

3D Cell Culture Technique

A next generation tumor research in translational medicine

Since decades cancer cell line has been promptly contributed significant understanding of physiology of heterogeneous tissue environment of cancer In the recent years threedimensional 3D cell culture technology has received a new dimension in tumor cell biology in identifying the biological characte..

Life-style, Environment, and Lack of Prediabetes Diagnosis Fueling Diabetic Epidemic

Lifestyle and environmentinduced metabolic derangement primes prediabetes stage with insulin resistance and increased BMI that eventually progresses to diabetes and NAFLD leading to CVD Prediabetes is a natural check point to prevent diabetic epidemic since 70 per cent of prediabetics develop diabet..

Multifunctional Nano-Cargo for Drug Delivery to Tumor Cells

Despite the advancements in tumor biology and medical research in tumor progression there is still a potential threat prevalent in the form of various diseases in human beings Nanotechnology however is in the developing stage for monitoring diagnosis and disease progression Nanomedicine rigorously f..

Cancer Stem Cell (CSC) Inhibitors

Marching Towards Curing Cancer?

Cancer is an incurable disease Cancer relapse is credited to a population of cells called as Cancer Stem Cells CSCs These drugresistant cells possess stemlike characters such as pluripotency selfrenewal and differentiation The latest trend in anticancer therapy is to eliminate CSCs so that cancer ca..

Enhancement of the Aqueous Solubility and Permeability of Poorly Water- Soluble Drugs

Drugs demonstrate a pharmacological intended role when its response is significant which depends upon the series of events and subsequent administration At the site of absorption drug solubility in the biological fluid is the ratelimiting step Most of the drugs developed these days posses a poor aqu..

Blood-Brain Barrier and CNS Drug Delivery

The central nervous system is protected by barriers which control the passage of various chemical substances and microscopic objects thereby regulating brain homeostasis This results in the incapability of existing pharmaceuticals to pass through the BloodBrain Barrier BBB Therefore the disorders re..

Nanocomposite Hybrid Metal-Organic Framework in Drug Delivery and Theranostic application

MetalOrganic Framework MOF comprises of metal ion coupled with organic ligands ie polymermetal nanocomposite which are a recent advances in chemistry for drug delivery and biomedical application The MOF is porous structure at nanoscale uses an innovative biomaterial which has compatible physicochem..

Nanotherapeutic Intervention in Cancer Disease

Cancer has been spreading worldwide consequently high number of deaths reported The therapeutic intervention involves surgical removal radiation therapy and chemotherapy The conventional technique in the drug regimen lack targeting potential and affecting normal cells of the body However nanomedicin..

Mesoporous Silica Nanoparticles

Applications and Apprehensions

Mesoporous silica Nanoparticles have been extensively investigated as Smart Drug Delivery System for various Biomedical applications including cancer treatment owing to its distinctive structure Biocompatibility and versatility Although extensive research findings are essential concerning toxicity s..