Structural Biology in Drug Discovery: Methods, Techniques, and Practices

Author(s) : Jean-Paul Renaud (Editor)

Book Description:

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field.

The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that:

    Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology
    Includes detailed chapters on druggability, allostery, co...

https://www.wiley.com/en-us/Structural+Biology+in+Drug+Discovery%3A+Methods%2C+Techniques%2C+and+Practices-p-9781118900505