Case Studies
Pharma case studies focus on specific issues and provide insights on how a particular technology or development is useful to the pharma companies. This section presents case studies on industry developments, technologies, products and services.
Evaluation of A Sequencing Batch Reactor Sewage Treatment Rig For Investigating The Fate of Radioactively Labelled Pharmaceuticals: A Case Study of Propranolol
Abstract Pharmaceuticals are frequently detected in the aquatic environment and have potentially damaging effects Effluents from sewage treatment plants STPs are major sources of these substances The use of sequencing batch reactor SBR STPs involving cycling between aerobic and anoxic conditions to promote nitrification and denitrification is incr...
Quality Management In Clinical Trials: An Observational Case Study By Pfizer
Abstract Clinical trials are conducted to collect the data necessary to provide information for academia industry and regulators to make decisions about the safety and efficacy of the disease illness or preventative medicines under study To ensure investigators are following the protocol complying with regulatory and G
Pediatrician’s Cough And Cold Medication Prescription For Hypothetical Cases: A Cross-Sectional Multi-Centric Case Study
Abstract Cough and cold is the most common cause for hospital visits and so is the use of cough and cold medication CCM A cough and cold medication has been considered to contain a single ingredient SI or multiple ingredients MI like promethazine PRZ chlorpheniramine CPM pseudoephedrine PS phenylephrine PE diphenhydramine DPH dextromethor
Effect Of Cold Spells And Theirmodifiers On Cardiovascular Disease Events: Evidence From A Double Prospective Study
Abstract Cardiovascular disease CVD is the most common cause of death globally remaining a considerable burden both in terms of health and costs As in many countries CVD mortality in the UK exhibits a marked seasonal variation more people die during the winter months DecemberMarch than in other periods of the year and the majority of deaths occur
A Dose-Escalation Case Study Of A Second-Generationnon-Ansamycin HSP90 Inhibitor, Onalespib (AT13387), Incombination With Imatinib In Patients With Metastaticgastrointestinal Stromal Tumour
Abstract Gastrointestinal stromal tumours GIST are commonly driven by activating mutations in the KIT or PDGFRA receptor tyrosine kinases Although the initial response rates for newly diagnosed GIST to the tyrosine kinase inhibitorTKI imatinib can be most tumours ultimately become resistant commonly through secondary mutations or through alterna...
Out-Of-Hours Antibiotic Prescription After Screening With C Reactive Protein: A Randomised Controlled Case Study
Abstract Fever respiratory symptoms and infections are common among children in primary care especially at outofhours OOH services Serious infections have low prevalence in primary care and even more so after introduction of vaccines for Haemophilus influenzae type B and pneumococcal conjugate vaccines It is challenging for clinicians to distingui...
Case Study: A Simple And Sensitive Method To Analyze Genotoxic Impurityhydrazine In Pharmaceutical Materials
Abstract Hydrazine NH is a known genotoxic impurity that typically needs to be controlled down to low ppm level in pharmaceutical development Hydrazine however is a challenging molecule to analyze using conventional analytical techniques due to its physical and chemical properties eg lack of chromophore absence of any carbon atom low molecular wei...
Effects Of Low-dose Ibuprofen Supplementation And Resistance Training On Bone And Muscle In Postmenopausal Women: A Randomized & Controlled Trial
Abstract Purpose To compare the effects of nine months of exercise training and ibuprofen supplementation given immediately after exercise sessions on bone and muscle in postmenopausal women Methods In a doubleblin
Regulating Pharmaceutical Industry Marketing: Development, Enforcement And Outcome Of Marketing Rules: A Case Study By Lund University
Abstract This essay studies work in sociology and cognate fields regarding pharmaceutical marketing and its regulation In particular it considers how this literature contributes to a better understanding of the process of pharmaceuticalization defined as the translation or transformation of human conditions capabilities and capacities into opportu...
Case Study: Has The Increase In The Availability Of Generic Drugs Lowered The Price Of Cardiovascular Drugs In South Africa?
Abstract The aim of this study was to examine the relationship between originator drug pricing and the number of available generic brands within the cardiovascular drug class in the context of SEP legislation and to compare South African drug prices with international drug prices Background
