Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of mycosessince. It is highly effective in the treatment of determatomycoses. The chemical and pharmaceutical analysis of the drug requires effective analytical methods for quality control and pharmacodynamic and pharmacokinetic studies. Ever since it was introduced as an effective antifungal agent, many methods have been developed and validated for its assay in pharmaceuticals and biological materials. This article reviews the various methods reported during the last 25 years.
Terbinafine hydrochloride; Analytical methods; Pharmaceuticals; Biological materials
Citation: Basavaiah Kanakapura, Vamsi Krishna Penmatsa Analytical Methods For Determination Of Terbinafine Hydrochloride In Pharmaceuticals And Biological Materials http://dx.doi.org/10.1016/j.jpha.2016.01.003
Received: 28 February 2015, Revised: 17 January 2016, Accepted: 25 January 2016, Available online: 25 January 2016
Copyright: © 2016 Xi'an Jiaotong University. Production and hosting by Elsevier B.V. This is an open access article
under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
One of the authors (Prof. K Basavaiah) is thankful to the University Grants Commission, New Delhi, India, for the award BSR Faculty Fellowship.