Better Wet Granulation: Development, Scale-up and Manufacture

By Tim Freeman, Freeman Technology

Wet granulation is a common unit operation in the pharmaceutical industry yet accurate endpoint detection remains a challenge. Here we examine the contribution that dynamic powder rheometry can make, highlighting its ability to detect the transition from wet mass to granulate with the required sensitivity. Quantification of this transition point, with a measure that is independent of process scale, accelerates development and scale-up and improves manufacture.

Download '.pdf' Format of the whitepaper.

Download Whitepapers
Latest Issue
Get instant
access to our latest e-book
Rousselot - X-PureĀ® || Modified Products The Live-to-Virtual Pivot 4 Best Practices Meco - 90 years Medical Fair Thailand 2022