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Biomarkers in Drug Discovery and Development: A Handbook of Practice, Application, and Strategy

Biomarkers in Drug Discovery and Development: A Handbook of Practice, Application, and Strategy

Pages: 608

Publisher: Wiley

Year of Publication: 2020

Author(s) : Ramin Rahbari (Editor), Jonathan Van Niewaal (Editor), Michael R. Bleavins (Editor)

Book Description:

This book continues the legacy of a well-established reference within the pharmaceutical industry – providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker characterization and validation and applications throughout drug discovery and development.

•    Explains where proper use of biomarkers can substantively impact drug development timelines and costs, enable selection of better compounds and reduce late stage attrition, and facilitate personalized medicine
•    Helps readers get a better understanding of biomarkers and how to use them, for example which are accepted by regulators and which still non-validated and exploratory
•    Updates developments in genomic sequencing, and application of large data sets into pre-clinical and clinical testing; and adds new material on data mining, economics, and decision making, personal genetic tools, and wearable monitoring
•    Includes case studies of biomarkers that have helped and hindered decision making
•    Reviews of the first edition: “If you are interested in biomarkers, and it is difficult to imagine anyone reading this who wouldn't be, then this book is for you." (ISSX) and “…provides a good introduction for those new to the area, and yet it can also serve as a detailed reference manual for those practically involved in biomarker implementation.” (ChemMedChem)

https://www.wiley.com/en-us/Biomarkers+in+Drug+Discovery+and+Development%3A+A+Handbook+of+Practice%2C+Application%2C+and+Strategy%2C+2nd+Edition-p-9781119187523

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