Chemical Exchange Saturation Transfer Imaging

Chemical Exchange Saturation Transfer Imaging

Pages: 300

Publisher: CRC Press

Year of Publication: 2016

Advances and Applications

Author(s) : Michael T. McMahon, Jeff W.M. Bulte, Assaf A. Gilad and Peter C.M. Van Zijl

Book Description:

Chemical Exchange Saturation Transfer is a powerful Magnetic Resonance Imaging (MRI) contrast mechanism with unique features. This is the first authoritative textbook covering all aspects of CEST imaging. The rapid expansion that CEST imaging has seen over the past 16 years since the seminal Ward and Balaban paper in 2000 has created a need for a graduate-level handbook that describes the wide assortment of issues that come in to play when trying to apply CEST imaging to medicine.


This textbook comprises 19 chapters which cover the fundamental principles of saturation transfer, the key features of CEST agents that enable production of imaging contrast, and practical aspects of preparing image acquisition and post-processing schemes suited for the application. It includes contributions from many internationally recognized experts and leaders in the fields of chemistry, physics, biochemistry and radiology.

This book also proffers a historical perspective is provided by leaders at the five key sites involved in the development of this technology, from the initial saturation transfer NMR experiments performed in the 1960’s in Stockholm, Sweden described by Sture Forsén, to the work applying the principles of saturation transfer to magnetic resonance imaging by Robert Balaban, Dean Sherry, Silvio Aime and Peter van Zijl in the USA and Italy applying the principles of saturation transfer to magnetic resonance imaging.