Modeling In Biopharmaceutics, Pharmacokinetics And Pharmacodynamics

Modeling In Biopharmaceutics, Pharmacokinetics And Pharmacodynamics

Pages: 483

Publisher: Springer International Publishing

Year of Publication: 2016

Author(s) : Macheras, Panos, Iliadis, Athanassios

Book Description:

The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body.

The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with epirical, compartmental, and stochastic pharmacokinetic models, with two new chapters, one on fractional pharmacokinetics and one on bioequivalence; and the fourth mainly with classical and nonclassical aspects of pharmacodynamics.