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Predictive Modeling of Pharmaceutical Unit Operations, 1st Edition

Predictive Modeling of Pharmaceutical Unit Operations, 1st Edition

Pages: 208

Publisher: Woodhead Publishing

Year of Publication: 2016

Author(s) : Preetanshu Pandey

Book Description:

Predictive Modeling of Pharmaceutical Unit Operations chronicles the progress this practice has made in the pharmaceutical industry in recent years. Modeling serves multiple purposes, not only enhancing process understanding, but also reducing experimentation and overall costs. Several process modeling tools have been used in the pharmaceutical industry, including DEM, FEM, CFD, population balance, and Monte Carlo, etc.

Modeling plays an important role in the QbD paradigm that is supported heavily by Food and Drug Administration (FDA). Once a good model is established, it can be used to create a process design space with minimal experimentation. This book focuses on modeling techniques pertinent to pharmaceutical unit operations that are commonly used in drug development of solid dosage forms.

Each individual chapter is dedicated to a single unit operation, starting with a short introduction to that unit operation that is then followed by a discussion of the techniques that have been successfully used to model that unit operation. Each chapter consists of multiple case studies where a certain model was applied successfully to a certain scenario in order to familiarize the reader with the application aspect of said model.

http://store.elsevier.com/product.jsp?isbn=9780081001547&pagename=search

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