Publisher: Academic Press
Year of Publication: 2024
Author(s) : Mitesh Dwivedi, DeLisa Fairweather
Regulatory T cells and Autoimmune Diseases addresses the role of Tregs in the pathogenesis of autoimmune diseases, along with therapeutic aspects. The book deals with the various Treg based mechanisms which can lead to autoimmune diseases and covers the different aspects of linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies. The book focuses on the Treg based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood & blood vessel, and eye diseases.Additionally, the book covers the vaccines induced effects on functioning of Tregs and development of CAR Tregs therapy for these autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. It is carefully designed to meet the requirements of both basic and advanced researchers in the area and give new dimensions and insight into the regulatory T cells’ role in autoimmune disease pathogenesis and therapeutic aspects.