Thursday, May 24, 2018
CENTOGENE, the worldwide leader in elucidating rare disease genetics for patients, clinicians and pharmaceutical partners, today announced a clinical development collaboration with Orphazyme A/S (CPH: ORPHA) to improve the lives of patients and families living with neuronopathic Gaucher disease, a rare, inherited, progressive and debilitating lysosomal storage disorder.
Under the terms of the agreement, CENTOGENE is supporting Orphazyme’s clinical trial efforts in India for the use of the small molecule, arimoclomol, for the treatment of neuronopathic Gaucher disease.
“Being able to monitor the treatment improvement in a clinical trial is a crucial capability for the pharmaceutical industry today. With our deep expertise in biomarker identification and development of diagnostic tools combined with our profound rare disease knowledge and global reach, we are ideally positioned to be the partner of choice for Orphazyme and drug developers worldwide,” said Dr. Arndt Rolfs, CEO and founder of CENTOGENE.
CENTOGENE is responsible for processing and analyzing a variety of different sample types from patients participating in the trial including plasma, cerebral spinal fluid and dried blood spots from CENTOGENE’s CentoCard®. Furthermore, CENTOGENE has developed and is using the most sensitive and validated biomarker for Gaucher disease, lysoGb1, as a monitoring tool during the trial.
