Pharma Focus Asia

Xencor Signs Four Commercial License Agreements with Selexis SA

Tuesday, February 27, 2018

Selexis SA, a pioneering life sciences company and a global leader in mammalian cell line generation technology, today announced that it has signed four commercial license agreements (CLAs) with Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer. The CLAs extend the companies’ previous agreement through which Selexis is providing Xencor with access to its SUREtechnology Platform™, as well as cell line development-related services that include personnel, laboratory equipment and laboratory space.

“The execution of these four CLAs represents a very important milestone in the continuum of the strategic agreement we signed with Xencor in 2016 in that it provides a means for Selexis to continue to help Xencor as Xencor advances its clinical candidates towards commercialization,” said Yemi Onakunle, PhD, MBA, Selexis vice president, licensing and business development. “This deepening relationship is a testament to the ability of our robust and predictable cell line platform to rapidly and reliably establish production-ready cell lines to advance Xencor’s pipeline of bispecific antibodies. We are excited by the opportunity to continue to grow with their business and witness the power of our synergistic technologies.”

The strategic business relationship between Selexis and Xencor began with a service agreement in 2011. In 2016, the two entered a new agreement through which Selexis scientists are collaborating with Xencor scientists and project leaders on selected multi-specific antibody gene expression and cell line development programs.

“Speed, reliability and flexibility are critical factors that we consider when seeking a partner to help us advance our programs,” said Edgardo Baracchini, PhD, MBA, chief business officer, Xencor. “Our relationship with Selexis has been very successful to date, so the decision to continue our work with the team was simple. Overall, the use of Selexis’ technologies and services significantly reduces the time, effort, and costs associated with developing high-performance cell lines. Their technology allows us to focus on leveraging the ‘plug-and-play’ nature of our bispecific antibody platform to deliver new treatment options to patients facing life-threatening diseases.”

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