Polymers are becoming increasingly important in the field of drug delivery. The pharmaceutical applications of polymers range from their use as binders in tablets to viscosity and flow controlling agents in liquids, suspensions and emulsions. Use of polymer is now extended to controlled release and targeting drug delivery system. Polymers are obtained from natural source as well as synthesized chemically. Polymers are classified as biodegradable and nonbiodegradable. Biodegradable polymers have been widely used in biomedical applications because of their known biocompatibility and biodegradability. The present review gives an overview of the different biodegradable polymers that are currently being used in the development of controlled drug delivery system.
Polymers possess a unique strength in their application towards drug delivery systems which enables the new advancement in the formulation of new drug delivery systems which improves the therapy and treatment. Biodegradable polymers have proven their potential for the development of new, advanced and efficient drug delivery system. They are capable of delivering a wide range of bioactive materials. From a polymer chemistry perspective, it is important to appreciate that the mechanisms of controlled-release require polymers with a variety of physico-chemical properties. Several types of polymers have been investigated as potential drug delivery systems, including Nano and micro-particles, dendrimers, Nano and micro-spheres, capsosomes and micelles. In these systems, drugs can be encapsulated or conjugated into polymer matrices to control the drug release.
Citation: Gavasane AJ, Pawar HA (2014) Synthetic Biodegradable Polymers Used in Controlled Drug Delivery System: An Overview. Clin Pharmacol Biopharm 3:121.doi: 10.4172/2167-065X.1000121
Received: September 08, 2014; Accepted: September 18, 2014; Published: September 22, 2014
Copyright: 2014 Gavasane AJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Authors are very much thankful to Dr. P. S. Gide, Principal, Hyderabad (Sindh) National Collegiate Board’s Dr. L.H.Hiranandani college of pharmacy, Ulhasnagar for his continuous support, guidance and encouragement.
Conflict of Interests: The author(s) declare(s) that there is no conflict of interests regarding the publication of this article.