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Biogen and Sage Therapeutics Introduce First-of-its-Kind ZURZUVAE™ for Postpartum Depression

Biogen has introduced first-of-its-kind ZURZUVAE™ (zuranolone) approved for adults with postpartum depression (PPD). This new treatment seems to be a significant step forward in addressing the needs of women who suffer from this condition.

ZURZUVAE is the first oral medication that offers rapid improvements in depressive symptoms over a 14-day treatment period, potentially providing relief as early as three days after starting the medication. 

ZURZUVAE's mechanism of action involves targeting the GABA-A receptor as a positive allosteric modulator (PAM), utilising the brain's major inhibitory signalling pathway to regulate brain function. This approach is noteworthy as it aims to address the underlying neurochemical imbalances associated with PPD.

The introduction of ZURZUVAE as the first and only oral, once-daily treatment specifically designed for postpartum depression is a groundbreaking development. The availability of a treatment can potentially lead to rapid improvements in depressive symptoms by making a significant difference in the lives of these women and their families.

US FDA clears ZURZUVAE™ (zuranolone) as first oral treatment for postpartum depression in women.

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