Techno Trends
TechnoTrends provide comprehensive coverage of the innovations and inventions in pharma products and pharma technologies across the world. The up-to-date listing of latest pharmaceutical product news and technology trends in the global pharma industry, keeps you abreast with all the latest pharmaceutical innovations happening world over.
Researchers Develop DNA-encoded PCSK9 Inhibitors to Regulate Cholesterol Levels in Bloodstream
<p xss=removed>The Wistar Institute researchers have developed novel synthetic DNA-encoded Monoclonal Antibodies (DMAbs) directed against PCSK9, a protein key to regulating cholesterol levels in the bloodstream.</p> <p xss=removed>A preclinical study showed a significant cholesterol decrease, helping for the development of this approach as a simple, less frequent and cost-effective therapy.</p> <p xss=removed>Elevated, Low-Density Lipoprote...
Molecule Discovery Shows Promise for Gene Therapy for Skin Diseases
<p xss=removed>University of Birmingham scientists announced the discovery of a protein that could hold the key to novel therapies for skin problems such as psoriasis.</p> <p xss=removed>The newly discovered protein, which is a fragment of a larger molecule, called JARID2 was present to only be present in the developing embryo, where it coordinates the formation of tissues and organs.</p> <p xss=removed>JARID2 is responsible for ensuring th...
Mount Sinai Researchers Determine Significant Beta Cell Proliferation Using Combination of Pharmacologic and Genetic Inhibition
<p xss=removed>Mount Sinai Researchers determines a significant beta cell proliferation using combination of pharmacologic and genetic inhibition.</p> <p xss=removed>They have discovered a novel combination of two classes of drugs that induces the highest rate of proliferation in adult human beta cells - the cells that produce insulin in the pancreas.</p> <p xss=removed>The result will help for the diabetes treatment that restores the body&...
Novartis Promacta® Approved as First-Line Treatment for Severe Aplastic Anemia(SAA)
<p>Novartis Promacta® is approved as the first-line treatment for adults and pediatric patients two years and older with Severe Aplastic Anemia (SAA) in combination with standard immunosuppressive therapy (IST).</p> <p>Promacta is an oral thrombopoietin receptor agonist (TPO-RA) that is already approved for SAA for patients who have had an insufficient response to IST.</p> <p>It can also be used for adults and children with chronic immune t...
NRX-101 Represents New Class of Antidepressants to Decrease Suicidal Thoughts
<p>NeuroRx's NRX-101, the first oral drug targeting suicidal bipolar depression helps to treat severe bipolar depression with Acute Suicidal Ideation & Behavior (ASIB).</p> <p>NRX-101 is used for treatment of Severe Bipolar Depression with Acute Suicidal Ideation & Behaviour after initial stabilisation with ketamine or other effective therapy.</p> <p>NRX-101 (D-cycloserine/lurasidone fixed dose combination) is the first oral drug demon...
Researchers Design and Develop New Class of Molecules to Halt Tumors
<p>Researchers at Stevens Institute of Technology and colleagues have designed and developed a new class of molecules that use a never-before-known mechanism that may halt or destroy breast cancer tumors.</p> <p>This mechanism can be used for patients with drug-resistant or dangerously metastatic stages of the disease.</p> <p>The molecule developed by the scientists could potentially add to the arsenal of drugs actively being developed to d...
Insmed Announces ARIKAYCE® For the Treatment of Mycobacterium Avium Complex (MAC) Lung Disease
<p xss=removed>Insmed, Inc. announced ARIKAYCE® (amikacin liposome inhalation suspension) for the treatment of Mycobacterium Avium Complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients.</p> <p xss=removed>ARIKAYCE can be used for patients with MAC lung disease, a chronic and debilitating condition that can significantly increase patient morbidity and mortality.</p> <p xss=removed>It is being asses...
NUS and Harvard Scientists Develop Novel Drug to Treat Liver Cancer Effectively
<p xss=removed>A team of Scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) developed a novel peptide drug called FFW to treat liver cancer effectively.</p> <p xss=removed>FFW could potentially stop the development of Hepatocellular Carcinoma (HCC) or primary liver cancer.</p> <p xss=removed>This discovery can be used for more effective treatment of liver cancer with less ...
Pfizer Launches Janus Kinase 3 (JAK3) Inhibitor PF-06651600
<p xss=removed>Pfizer launched its investigational oral Janus Kinase 3 (JAK3) inhibitor PF-06651600, which is used for the treatment of patients with alopecia areata.</p> <p xss=removed>Alopecia areata is chronic autoimmune skin disease in which immune cells attack healthy hair follicles, causing hair loss in round patches and causes hair loss on the scalp, face, or body.</p> <p xss=removed>The mean age for the disease’s onset is between 25...
Alnylam’s ONPATTRO to Treat Patients with Hereditary ATTR Amyloidosis in Adults
<p xss=removed>Alnylam’s ONPATTRO™ (patisiran) lipid complex injection is a first-of-its-kind RNA interference (RNAi) therapeutic used to treat the polyneuropathy of hereditary transthyretin-mediated (hATTR) Amyloidosis in adults.</p> <p xss=removed>RNAi is a completely new approach to the treatment of these diseases; targeting the faulty protein that is causing the disease rather than treating the symptoms. RNAi therapeutic is an entirely new...
