Research Insights

Research Insights section focuses on the cutting-edge and breakthrough research that is happening all over the world. Laboratories across the globe are working hard to develop drugs and therapies for various diseases and research insights directly from them add tremendous value.

The Economic Burden of Antibiotic Resistance: A Systematic Review and

Antibiotic resistance ABR has substantial global public health concerns This systematic review aimed to synthesise recent evidence estimating the economic burden of ABR characterised by study perspectives healthcare settings study design and income of the countries

A Hybrid Technique for Measurement of Intra/extracellular Proteins

ELISA or Western blot is known as a basic technique to be used for measurement of intracellular proteins but in some cases they cannot overcome problems such as normalization between samples or extraneous costs for required commercial kits

Antisense Oligonucleotides to Therapeutically Target SARS-CoV-2 Infection

Although the COVID pandemic began over three years ago the virus responsible for the disease SARSCoV continues to infect people across the globe

High Glucose Promotes Regulatory T Cell Differentiation

The consumption of processed foods and sugary sodas in Western diets correlates with an increased incidence of obesity metabolic syndromes such as type diabetes cardiovascular diseases

A Proteomic Perspective and Involvement of Cytokines in SARS-CoV-2 Infection

Infection with the SARSCoV virus results in manifestation of several clinical observations from asymptomatic to multiorgan failure

A Multiple Instance Learning Approach for Detecting COVID-19 in Peripheral

A wide variety of diseases are commonly diagnosed via the visual examination of cell morphology within a peripheral blood smear

Interactome Overlap Between Risk Genes of Epilepsy and Targets of Anti-epileptic

Aantiepileptic drugs have been used for treating epilepsy for decades meanwhile more than one hundred genes have been identified to be associated with risk of epilepsy

An Evaluation of RNA-seq Differential Analysis Methods

Highthroughput transcriptome sequencing technologies have profound impact on our ability to address an increasingly diverse range of biological and biomedical problems and improve our understanding of human diseases by capturing an accurate picture of molecular processes within the cell RNAseq has become a major assay for measuring relative transcr...

Connectivity Concepts in Neuronal Network Modeling

The connectivity structure of a neuronal network model is sometimes described with a statement such as Ns source neurons and Nt target neurons are connected randomly with connection probability p One interpretation of this statement is an algorithm that considers each possible pair of source and target neurons exactly once and connects each such pa...

Human Genotype-to-phenotype Predictions Boosting Accuracy with Nonlinear Models

The problem of predicting phenotype from genotype is a holy grail of modern genetics with practical applications in fields such as personalized medicine and genomic selection for agriculture and is an active area of research Its relevance has grown with the affordability of genotyping and will likely continue to increase as sequencing becomes more...