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Sep 2018MEBIAS Discovery Receives Grant from NIDA to Advance Its Signaling-Pathway Selective Mu-Opioid Receptor Drug Candidate
MEBIAS Discovery an emerging leader in the field of drug discovery targeting Gprotein coupled receptors has secured grant funding from the National Institute of Drug Abuse NIDA to progress a muopioid receptor candidate Preclinical data presented last year at the Academic Drug Discovery Consortium revealed…
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Sep 2018Seattle Genetics Announces ADCETRIS® (Brentuximab Vedotin) Approval in Japan for Frontline Hodgkin Lymphoma
Seattle Genetics Inc today announced that its collaborator Takeda Pharmaceutical Company Limited Takeda has received approval from the Japanese Ministry of Health Labour and Welfare for ADCETRIS brentuximab vedotin in combination with doxorubicin vinblastine and dacarbazine AVD as a frontline treatment option for CDpositive Hodgkin…
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Sep 2018Cardurion Pharmaceuticals Announces Initiation of Phase 1 Study of CRD-733, a PDE-9 Inhibitor in Development for the Treatment of Heart Failure
Cardurion Pharmaceuticals a biotechnology company focused on the development of novel nextgeneration therapeutics for the treatment of cardiovascular diseases today announced that the US Food and Drug Administration FDA has accepted its Investigational New Drug Application IND for CRD a Phosphodiesterase PDE inhibitor in development…
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Sep 2018Takeda receives favorable opinion from the CHMP for ALUNBRIG ® (Brigatinib) for the treatment of ALK-positive non-small cell lung cancer in crizotinib-treated patients
Takeda Pharmaceutical Company Limited announced today that the Committee for Medicinal Products for Human Use CHMP of the European Medicines Agency EMA has issued a favorable opinion Approval of ALUNBRIG…
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Sep 2018Teenager’s Lifesaving TickTracker App Recognized by Department of Health & Human Services
Denver Colo Sept GLOBE NEWSWIRE The new mobile application TickTracker created by Colorados yearold Olivia Goodreau will be joining a week tech development sprint lead by the Department of Health…
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Sep 2018Leading Online Supplement Marketplace HealthXP Signs Sahil Khan as Its Brand Ambassador in India
Business Wire IndiaHealthXP Indias fastest growing online health nutrition and sports supplement store is proud to announce its association with fitness icon Mr Sahil Khan in India Mr Khan who…
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Sep 2018Safety Labeling and Packaging
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Sep 2018Cosmetics Compliance
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New York
TOP ARTICLES
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1
Are you Ready for EU FMD?
With the deadline looming for enactment of EU FMD and US DSCSA Vikash Pushpraj Senior Vice President rfxcel explains how achieving compliance is about much more..
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2
Life-style, Environment, and Lack of Prediabetes Diagnosis Fueling Diabetic Epidemic
Introduction For the past ten years ample evidence exists to suggest that what we eat and how we live determines how our body and genes behave A rapid rise i..
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3
Cancer Stem Cell (CSC) Inhibitors
Cancer as a group of heterogeneous diseases very well known Unimaginable amounts of money and manhours have been spent in finding cure for this deadly disease H..
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4
Enhancement of the Aqueous Solubility and Permeability of Poorly Water- Soluble Drugs
Introduction Combinatorial chemistry High Throughput Screening technique HTS and other computeraided methods have proved their usefulness for drug design and..
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5
Blood-Brain Barrier and CNS Drug Delivery
Introduction The idea of Blood Brain Barrier BBB dates back to more than years ago when Paul Erlich observed that by intravenous injection of certain dyes all..
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6
Nanocomposite Hybrid Metal-Organic Framework in Drug Delivery and Theranostic application
Introduction MOFs are evolving novel hybrid materials comprised of two component of inorganic and an organic fraction with diverse physicochemical characteris..
Knowledge Bank
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Interviews
Merck
Staff Engineer, Manufacturing Science and Technology, South East Asia
Karen Chan is a process engineer at Merck Pte Ltd Chan has six years of experience in the biopharmaceutical industry and two years of experience in research development She provides technical support in areas such as process development troubleshoot..
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Articles
Oral Formulation of Bio-pharmaceuticals
Introduction There are several key factors making oral delivery systems the most attractive delivery route for pharmaceutical researchers and industry In addition to patients compliance oral delivery provides advantages such as a very large surface area for drug absorption about m elimination of hazardous wastes and applicability for solid drug formulations Furthermore the availability…
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Research Insights
Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine
Abstract Background Inflammatory breast cancer IBC is a rare aggressive form of breast cancer associated with HER amplification with high risk of metastasis and an estimated median survival of y We performed an openlabel singlearm phase II clinical trial ClinicalTrialsgov NCT to investigate the efficacy and safety of afatinib an irreversible ErbB family inhibitor alone and in combination with vinorelbine…
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Case Studies
Rapid, Comprehensive, And Aff Ordable Mycobacterial Diagnosis With Whole-genome Sequencing: A Prospective Case Study
Abstract Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex MTBC risk delayed treatment and poor patient outcomes Wholegenome sequencing WGS could potentially provide a rapid and comprehensive diagnostic solution In this prospective study we compare realtime WGS with routine MTBC diagnostic workflows Methods We compared…
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Techno Trends
World's First Metal-based Probes for Detection of Dopamine Receptors - Developed by HKBU Researchers
A team of researchers of Hong Kong Baptist University has developed the worlds first metalbased probes for the identification of dopamine receptors in living cells This breakthrough innovation helped the researchers to understand the dopamine receptors in carcinogenesis Dopamine is an organic chemical of the catecholamine and phenethylamine which act as an important neurotransmitter in the central nervous system of…
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White Papers
Launching Global Clinical Trials—best Practices For Efficient And Cost-effective Translations: A Lionsbridge White Paper
Summary The target market for conducting global clinical trials has changed significantly moving beyond pharmaceutical early adopters to the mainstream marketplace This shift has placed a heightened focus on the language challenges and complexity of running a global clinical trial More and more companies are moving toward ascending regions such as India and China to…
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Industry Reports
Sanochemia Pharmazeutika AG (SAC) - Financial and Strategic SWOT Analysis Review
Sanochemia Pharmazeutika AG Sanochemia is a specialty pharmaceutical company that develops and manufactures of innovative drugs and diagnostics in selected indication areas such as neurodegeneration pain and cancer as well as diagnostic products based on contrast media The companys product portfolio includes radiological products including an array of xray imaging…
Advisory Board
Editorial Section
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Strategy
Statin Drug Interactions and Related Adverse Reactions
Statins are generally well tolerated with a low frequency of adverse events but since statins are prescribed on a longterm basis many patients will typically receive pharmacological therapy for concomitant conditions during the course of statin treatment and potentially interacting…
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Research development
Stem Cell and Gene Delivery
These days gene and stem cell therapies have the potential to make the substantial impact on the treatment of several diseases However there are pros and cons of each strategy but the optimal selection of gene delivery vector or stem…
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Clinical Trials
Managing Clinical Trial Agreements
Clinical Trial Agreements set out how a clinical trial will be run at the site and are an essential GCP document There are a number of key factors that determine whether a Clinical Trial Agreement is successful in achieving that…
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Manufacturing
Drug Concentration Assurance of Continuous Tablet Manufacturing
In the pharmaceutical industry Real Time Release RTR can be facilitated by the development of a highly efficient control system The drug concentration in final tablet is one of the most critical quality attributes that…
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Information Technology
R&D DATA HUB
Faster decision making and better trial oversight at all levels requires truly next generation data integration and analytics Source and format agnostic data aggregation aided by modern data lake architecture and advanced analytics deliver interactive…
