KNOWLEDGE BANK

Interviews

How can bioprinting enable better drug discovery?

CEO, Axolotl Biosciences
Dr Stephanie Willerth is a biomedical engineer entrepreneur and thought leader in D bioprinting and neural tissue engineering As CEO of Axolotl Biosciences and a Full Professor at the University of Victoria she leads innovations in personalized medicine through bioink development and human tissue models Her work bridges academia and industry bringing groundbreaking research into realworld healthca...

Articles

There’s Finally Hope to Alleviate the Burden of Chronic Diseases

As societies in Asia grow older chronic diseases are becoming more and more prevalent They place serious strain not only on patients but also on caregivers and the healthcare system

Research Insights

Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release

Hepatitis C virus HCV causes acute hepatitis C and can lead to lifethreatening complications if it becomes chronic The HCV genome is a single plus strand of RNA Its intracellular replication is a spatiotemporally coordinated process of RNA translation upon cell infection RNA synthesis within a replication compartment and virus particle production

Case Studies

Local Production Of Pharmaceuticals And Related Technology Transfer In Developing Countries

Abstract As stakeholders in the Global Strategy and Plan of Action on Public Health Innovation and Intellectual Property GSPAPHI adopted by the World Health Assembly in the United Nations Conference on Trade and Development UNCTAD the World Health Organization WHO and the International Centre for Trade and Sustainable Development ICTSD are col

Techno Trends

Susvimo™, Breakthrough Therapy Discovered for Wet Age-Related Macular Degeneration (nAMD)

Roche discovered breakthrough therapy Susvimo ranibizumab injection for the treatment of people with neovascular or wet agerelated macular degeneration nAMD Susvimoearlier known as port delivery system with ranibizumab is the first and only alternative treatment in years which provides standardofcare

White Papers

Cloud Computing in the Laboratory Informatics Solutions and Validation Approaches

In the modern business environment, a significant portion of work is conducted using computerized systems. Many solutions are used to complete tasks, including simple desktop programs like email and Microsoft Office to enterprise-wide, global systems like ERP (Enterprise Resource Planning), MES (Manufacturing Execution System), and LIMS

TOP ARTICLES

1

Nano-Carrier based Smart Drug Delivery Systems

Sidharth Mehta

Sidharth Mehta, Researcher in Market Research domain at Prescient Healthcare Group, India. He is a Master’s in Pharmacy (Pharmaceutics) by qualification did his postgraduation from GJUS&T, Hisar, India. His research interests are mainly in the field of nanotechnology. In 2021, he spent a period at University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh (India) with an UGC-NRC project on “Development and Evaluation of Solid Lipid Nanoparticles as Drug Carrier for Topical Delivery of Leflunomide”. He has published several papers in international peer reviewed journals. He had done in-plant training in two pharmaceutical companies and improved his research skill as per industry standards. He worked hard on both his academic and practical skills, as a result of that he qualified national level pharmacy graduate test (GPAT) thrice and NIPER with good rank.

 

Nikita Yadav

Nikita Yadav, she believes that you can achieve anything at any age. She is a Master’s in Pharmacy (Pharmaceutics) by qualification did her postgraduation from GJUS&T, Hisar, India. Her research interests are mainly in the field of nano- and micro-technology with the use of essentials and natural ingredients.  She had many recent experiences like a course in Elsevier[Certified peer reviewer Course], in Good Clinical Practice by NIDA Clinical trials networkandin Regulatory affairs by Udemy.Also, she joined an NGO i.e., Aashman Foundation, which mainly work unconditionally on women empowerment, single income families and underprivileged children through relevant healthcare, innovative education, and environmental based livelihood programs. She also qualified national level pharmacy graduate test (GPAT) in 2020.

 

2

From Gene Editing to Network Medicine

Prof. Dr. Hemanth Kumar Manikyam

Prof. Dr. Hemanth Kumar Manikyam is a researcher in natural products chemistry and systems pharmacology. He is widely known as the father of Intrinsic Network Pharmacology (INP), an integrative framework combining artificial intelligence, biological network analysis, and traditional medicinal knowledge to explore complex therapeutic mechanisms and next-generation precision medicine.

3

Determinants of Antimicrobial Resistance (AMR) Research in South East Asia

Raja Chakraverty

Raja Chakraverty is a serving Scientist with the Indian Council of Medical Research with a decade long research and teaching career in Pharmaceutical Sciences with 54 publications (186 citations) and a book

 

Tatini Debnath

Doctoral Scholar, Department of Pharmaceutical Technology

4

Redefining Therapeutics

Mads Hald Andersen

Professor Mads Hald Andersen, DMSc, DScTech, PhD, is Director of the National Center for Cancer Immune Therapy, CCIT-DK, at Copenhagen University Hospital Herlev, Denmark. He discovered tumor microenvironment antigens and anti-regulatory T cells and defined their role in immune regulation. He initiated the immune modulatory vaccine concept and has authored more than 250 publications and 25 patents.

5

Single Domain Antibody

Marco Pirisinu

Dr. Marco Pirisinu graduated from the University of Sassari, Italy, with a degree in Biomedical Sciences focusing on the novel design and application of cell penetrating peptide targeting mitochondria. He has more than 10 years of research experience working with academic institutions and biotechnology companies. His primary research interest are nanomedicine, targeted therapy and drug delivery systems. Dr. Pirisinu is first author and corresponding author of peer reviewed articles and Guest Editor forSCI-indexed journals. He is currently Senior Scientist at City University of Hong Kong and Head of Innovative Product Development at Jotbody (HK) Limited.

 

Likun Wei

Dr. Likun Wei obtained his BEng from Tianjin University of Technology, majoring in computer science and MSA from Shanghai Ocean University, majoring in agriculture.He completed his PhD in Biomedical Sciences at City University of Hong Kong in 2021. His PhD work demonstrated a small shark model for affordable high affinity sdAb production.He has co-authored 12 publications in SCI-indexed journals including Nature Communications, Bioresource Technology, Journal of Extracellular Vesicles, Iscience, The Journal of Immunology, and Frontiers in Bioengineering and Biotechnology.  Dr. Likun Wei is currently R&D Lead at Jotbody (HK) Limited.

 

press releasesRead more...

IMPACT Therapeutics Signs Exclusive License Agreement with Pharmanovia for Senaparib in Europe, Middle East and North Africa, Australia and New Zealand

IMPACT Therapeutics IMPACT HK is pleased to announce that it has entered into an exclusive partnership the Exclusive Partnership with Pharmanovia a global specialty pharmaceutical company

FDA approves Pluvicto for PSMA+ metastatic hormone-sensitive prostate cancer (mHSPC), advancing potential new standard of care across metastatic disease

Novartis today announced the US Food and Drug Administration FDA approved Pluvicto lutetium Lu vipivotide tetraxetan in combination with an androgen receptor pathway inhibitor ARPI for patients

Ractigen Therapeutics Closes Over $31 Million Financing to Advance Clinical-Stage saRNA Pipeline and Proprietary Extrahepatic Delivery Platforms

Ractigen Therapeutics a clinicalstage biotechnology company pioneering small activating RNA saRNA therapeutics and advanced extrahepatic delivery systems today announced the successful closing of a new financing round exceeding million over RMB million

Insilico Medicine Launches the Industry's First Drug Discovery and Development (DDD) Benchmark as a Service, to Evaluate Frontier AI and Foundation Models on Real-World Science

As generalpurpose and domainspecific AI models rapidly infiltrate drug discovery one critical question looms over the pharmaceutical sector Can these models actually discover drugs or are they just good at taking tests

HKEY-AI2Vivo™ 1.0: HKeyBio Accelerates In Vivo Translation for AI-Designed Candidates

HKeyBio has established HKEYAIVivo its AI Candidate In Vivo Validation Acceleration Program The program supports AI drugdiscovery teams in translating AIgenerated targets

Medidata Launches Medidata Plus, an AI-Native Foundation Built to Scale Clinical Portfolios

Medidata a Dassault Systmes brand and leading provider of clinical trial solutions today announced the launch of Medidata Plus This clinical artificial intelligence layer unlocks the full breadth of AI capabilitie

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LATEST NEWSRead more...

CREATE Medicines Expands In Vivo CAR Platform Through Monash University Collaboration

CREATE Medicines has entered into a strategic research collaboration and exclusive licensing agreement with Monash University and its Monash Institute of Pharmaceutical Sciences MIPS to strengthen its targeted in vivo Chimeric Antigen Receptor CAR therapy platform

Kaigene Licenses Autoimmune Therapy KG006 to Taisho Pharmaceutical for Japan

Kaigene a USbased biotechnology company focused on antibody therapies for autoimmune diseases has signed an exclusive licensing agreement with Taisho Pharmaceutical for the development and commercialisation of its nextgeneration human neonatal Fc receptor hFcRn inhibitor

EVERSANA to Support US Commercialisation of Innovacell’s ICEF15 Cell Therapy

EVERSANA has been selected by Tokyobased biotechnology company Innovacell as its exclusive commercialisation partner in the United States to support the planned launch of ICEF a regenerative cell therapy for urgent faecal incontinence

Ember LifeSciences and Alfresa Form Strategic Alliance to Strengthen Pharmaceutical Cold Chain in Japan

Ember LifeSciences has entered into a capital and business alliance with Alfresa Corporation to enhance pharmaceutical cold chain logistics in Japan As part of the agreement

AbCellera and Vertex Partner to Develop Multispecific T-Cell Engagers for Autoimmune Diseases

AbCellera has entered into a collaboration with Vertex Pharmaceuticals to discover develop manufacture and commercialise multispecific Tcell engagers TCEs for the treatment of autoimmune

Shionogi Launches XOCOVA in the U.S. for Prevention of COVID-19 Following Exposure

Shionogi has announced the US availability of XOCOVA ensitrelvir the first and only oral antiviral approved to help prevent COVID after exposure The treatment is indicated for adults and adolescents aged years