Pharma Articles
Articles on key issues related to the pharma industry from the heads of leading pharmaceutical companies and pharma industry experts across the globe. The pharma industry articles' section focuses on current and emerging issues in areas such as Strategic developments in the pharma industry, pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical manufacturing, biopharmaceuticals, and information technology.
Reshaping the Clinical Trial Model
A Call for Integration, Innovation, and Data-Driven Design
If we were to reimagine how we conduct clinical trials today would we use the same methods weve relied on for decades I would argueabsolutely not The traditional model while foundational is no longer fit for purpose in a world where technology data and patient expectations are evolving rapidly To tr...
Trump Tariff Tyranny and Pharma Preparedness
On August President Trump announced the imposition of an additional per cent tariff on India specifically linked to its continued purchase of Russian oil This move has effectively increased the overall tariff burden on Indian exports to the United States to nearly per cent The sectors most affect...
Peptide-Drug Conjugates in Precision Oncology
Engineering next-generation targeted therapies
Cancer therapies have evolved from broadly cytotoxic agents to increasingly refined and targeted treatments Amidst this transformation peptidedrug conjugates PDCs have emerged as a promising class of bioconjugates that offer the precision of targeted delivery combined with the potency of cytotoxic d...
Generative AI and the New Era of Personalized Medicine
For decades drug discovery has been one of sciences most laborious and expensive pursuits Despite extraordinary progress in chemistry and biology most candidate molecules that enter clinical trials fail to become approved medicines The process is slow costly and heavily dependent on luck and trialan...
Precision medicine for Alzheimer’s Disease
Emerging Paradigm in Genomics, Biomarkers & AI tools
Alzheimers disease a common cause of dementia is characterised by deposition of senile plaques and neurofibrillary tangles These protein deposits are inherent key features of AD distinguishing from other types of dementia AD also notably marks with neuroinflammation oxidative stress
Nanotechnology based Drug Delivery for Infectious Diseases
Infectious diseases continue to pose a serious threat to global health particularly in the face of rising antimicrobial resistance AMR emerging viral outbreaks COVID and neglected tropical diseases with an estimated million fatalities linked to bacterial AMR in The WHO research agenda for antimicr...
The Growing Role of Biocatalysis in Industrial Synthesis
Since the late th century chemical catalysis has been a cornerstone of organic synthesis and pharmaceutical manufacturing driving the development and mass production of key therapeutic molecules across multiple disease areas Despite its broad adoption and long history traditional organic synthesis t...
Natural Polymers and Fibers in Drug Delivery
Advancements in drug delivery have become increasingly critical due to the growing demand for more effective targeted and personalized therapies Modern drug delivery systems are designed not only to enhance the bioavailability and release of drugs but also to optimise pharmacokinetic parameters such...
Green Synthesis of Metallic Nanoparticles
A Sustainable Leap in Pharmaceutical Nanotechnology
Nanotechnology has transformed the pharmaceutical landscape offering revolutionary solutions in drug delivery diagnostics and therapeutics However traditional methods of synthesizing nanoparticles often rely on hazardous chemicals consume high energy and generate toxic byproducts As the industry lea...
Unlocking New Avenues in Cancer Therapy by Targeting Ubiquitin-Specific Proteases
The ubiquitinproteasome system UPS is a crucial mechanism that helps maintain balance within our cells by breaking down damaged or excess proteins Central to this process is ubiquitination where a small protein called ubiquitin made up of amino acids attaches to target proteins thus influencing the...
Impact Assessment of US Tariff Threat on Indian Healthcare Export
The ongoing tariff fusillades and retorts by the economies like China have precipitated several conundrums and made the trade future nebulous The flat per cent of reciprocal tariff across the sectors include the medical device also The pharmaceutical sector has been kept exempted The current tariff...
Revolutionising Tuberculosis Treatment test
Innovative drug delivery approaches
Tuberculosis TB is a contagious and often deadly infectious disease caused by the bacterium Mycobacterium tuberculosis While it primarily affects the lungs pulmonary TB the infection can also spread to other parts of the body such as the lymph nodes bones kidneys and brain extrapulmonary TB TB remai...
Tobacco-style Label Warning on Alcohol Products
An urgent call to combat cancer
Alcohol consumption is a major cause of death globally and the worst part of it is that there is a significant amount of unawareness even in the regions like Europe and the US Based on the different types of scientific studies like metaanalysis SLR observational in vivo preclinical and genetic studi...
The Role of Genomics in Shaping the Future of Medicine
Sequencing of the Human Genome at the beginning of the st century followed by the technological advances in Next Generation Sequencing NGS bioinformatics analysis tools and computational fire power have helped in making sequencingbased tests affordable and accessible for diagnostics and research pur...
Allosteric Modulation: A Paradigm Shift in Pharmaceutical Innovation
Allostery the regulation of a proteins function through the binding of a molecule at a site distinct from the active site has emerged as a pivotal concept in drug discovery By targeting allosteric sites researchers can modulate protein activity with high specificity potentially reducing offtarget ef...
