Research Insights

Research Insights section focuses on the cutting-edge and breakthrough research that is happening all over the world. Laboratories across the globe are working hard to develop drugs and therapies for various diseases and research insights directly from them add tremendous value.

Statistical Designs for Assessing Interchangeability of Biosimilar Products

More and more biopharmaceutical andor biotech companies begin to concern regulatory approval of biosimilar products due to some innovator products will expire in decades Once more biological products are going off patient the problem whether approving biosimilar products used interchangeably and safely will be considered Using a biological product...

RNAi Therapeutic Platforms for Lung Diseases

Yu Fujita Fumitaka Takeshita Kazuyoshi Kuwano and Takahiro Ochiya Division of Molecular and Cellular Medicine National Cancer Center Research Institute Tokyo Japan Division of Respiratory Diseases Department of Internal Medicine Jikei University School of Medicine Tokyo Japan

Publication of Clinical Trials Supporting Successful New Drug Applications: A Literature Analysis

Department of Clinical Pharmacy University of California San Francisco San Francisco California United States of America Department of Epidemiology and Biostatistics University of California San Francisco San Francisco California United States of America Division of General Internal Medicine University of California San Francisco San Francisco C...

Factors Associated with Findings of Published Trials of Drug-Drug Comparisons: Why Some Statins Appear More Efficacious than Others

Kristian Pietras Jessica Pahler Gabriele Bergers Douglas Hanahan Department of Biochemistry and Biophysics Diabetes Center and Comprehensive Cancer Center University of California San Francisco San Francisco California United States of America Ludwig Institute for Cancer Research Karolinska Institutet Sto

Boosting BCG with Recombinant Modified Vaccinia Ankara Expressing Antigen 85A: Different Boosting Intervals and Implications for Efficacy Trials

Ansar A Pathan Clare R Sander Helen A Fletcher Ian Poulton Nicola C Alder Natalie E R Beveridge Kathryn T WhelanAdrian V S Hill Helen McShane Centre for Clinical Vaccinology and Tropical Medicine University of Oxford Churchill Hospita

Factors Associated with Findings of Published Trials of Drug-Drug Comparisons: Why Some Statins Appear More Efficacious than Others

Lisa Bero Fieke Oostvogel Peter Bacchetti Kirby Lee Clinical Pharmacy and Health Policy University of California San Francisco California United States of America Department of Mathematics University of Leiden The Netherlands Department of Epidemiology and Biost

Optimizing the Dose of Pre-Pandemic Influenza Vaccines to Reduce the Infection Attack Rate

Steven Riley Joseph T Wu Gabriel M Leung Background The recent spread of avian influenza in wild birds and poultry may be a precursor to the emergence of a like human pandemic Therefore stockpiles of human prepandemic vaccine targeted at avian strains are being consider

Thermoresponsive Drug Delivery Using Liquid Crystal-Embedded Cellulose Nitrate Membranes

Rassoul Dinarvand A A Elham Khodaverdi A Fatemeh Atyabi A Mohammad Erfan A A Department of Pharmaceutics Faculty of Pharmacy Tehran University of Medical Sciences Tehran Iran A Pharmaceutical Sciences Research Centre Tehran University of Medical

Feasibility and Cost-Effectiveness of Treating Multidrug-Resistant Tuberculosis: A Cohort Study in the Philippines

Thelma E Tupasi Rajesh Gupta Ma Imelda D Quelapio Ruth B Orillaza Nona Rachel Mira Nellie V Mangubat Virgil Belen Nida Arnisto Lualhati Macalintal Michael Arabit Jaime Y Lagahid Marcos Espinal Katherine Floyd

Pharmacovigilance program to monitor adverse reactions of recombinant streptokinase in acute myocardial infarction

Blas Y Betancourt Mara A MarreroMiragaya Giset JimnezLpez Carmen ValenzuelaSilva Elizeth GarcaIglesias Francisco HernndezBernal Francisco DebesaGarca Tania GonzlezLpez Leovaldo AlvarezFalcn Pedro A LpezSaura