Pharma Articles
Articles on key issues related to the pharma industry from the heads of leading pharmaceutical companies and pharma industry experts across the globe. The pharma industry articles' section focuses on current and emerging issues in areas such as Strategic developments in the pharma industry, pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical manufacturing, biopharmaceuticals, and information technology.
3D Cell Culture Technique
A next generation tumor research in translational medicine
Introduction Tumor cell culture as one of the vital technique utilised in tumor cell biology for estimation of potentiality of developed formulation or newly established chemical entity or therapeutics in cancer cell killing The two dimensional monolayer cell cultures has certain limitation of be...
Life-style, Environment, and Lack of Prediabetes Diagnosis Fueling Diabetic Epidemic
Introduction For the past ten years ample evidence exists to suggest that what we eat and how we live determines how our body and genes behave A rapid rise in diabetic population noticed during the past thirty years has largely been attributed to lifestyle and physical inactivity While the lifest...
Multifunctional Nano-Cargo for Drug Delivery to Tumor Cells
Introduction Although multiple therapies are used in treating cancer disease amongst affected individuals it still continues to be progressing worldwide Conventional chemotherapy instead of achieving a positive outcome waiting for a longer time it rather worsens the condition as evident from case...
Cancer Stem Cell (CSC) Inhibitors
Marching Towards Curing Cancer?
Cancer as a group of heterogeneous diseases very well known Unimaginable amounts of money and manhours have been spent in finding cure for this deadly disease Howeverit still remains in the top five list of diseases affecting mankind Millions of patients suffer worldwide every single day hoping to g...
Enhancement of the Aqueous Solubility and Permeability of Poorly Water- Soluble Drugs
Introduction Combinatorial chemistry High Throughput Screening technique HTS and other computeraided methods have proved their usefulness for drug design and development with requisite pharmacological activity Bajaj et al To attain increased potency receptor binding is utmost important where rec...
Blood-Brain Barrier and CNS Drug Delivery
Introduction The idea of Blood Brain Barrier BBB dates back to more than years ago when Paul Erlich observed that by intravenous injection of certain dyes all organs of the animal body were stained except the brain and the spinal cord The densely packed brain endothelial cells are the main part of...
Nanocomposite Hybrid Metal-Organic Framework in Drug Delivery and Theranostic application
Introduction MOFs are evolving novel hybrid materials comprised of two component of inorganic and an organic fraction with diverse physicochemical characteristics MOFs have a high degree of porosity size tunability biocompatibility biodegradability and functionalisation capabilities Structurally M...
Nanotherapeutic Intervention in Cancer Disease
Introduction Cancer is second most prevalent and lethal disease after cardiovascular disorder despite of advances in tumor biology research and chemotherapy The nanotechnology tremendously growing with due advances in nanomedicine and drug delivery system The mantra of nanotherapy in cancer based o...
Mesoporous Silica Nanoparticles
Applications and Apprehensions
Mesoporous Silica Nanoparticles MSNs have attracted great attention over the last decade as a drug delivery system in the fields of biotechnology and Nano medicine due to their unique and adjustable physiochemical properties MSNs were first synthesised by Mobil researchers in and were called Mobil...
Antimicrobial Stewardship Prioritising Quality Access to Healthcare
Antimicrobials treatments that kill or inhibit the growth of microorganisms are effective and necessary in medicine However organisms and microbes have increasingly begun to resist antimicrobial agents through evolutionary change and mutations Resistance to antimicrobials creates a difficult path fo...
The European Lead Factory
A working model for collaborative public-private drug discovery
In drug discovery the search for new chemical equity to be developed into valuable preclinical and clinical candidates is very time and costintensive This is a particular difficulty for academics or small and medium enterprises SMEs who are likely to have limited resources Additionally small compani...
FPS Taylor made containment equipments
The higher activity and potency of new Pharmaceutical APIs HAPI s and Sterile products brings the request for tailor made containment solutions to priority level This is required to continuously meet the safety standard and to assure the requested level of advanced technology supporting research act...
Nanotechnology-based Inhalation Treatment for Lung Cancer
The lungs are the primary organ of the respiratory system The respiratory system works with the circulatory system to deliver oxygen from the lungs to the cells and remove carbon dioxide and return it to the lungs to be exhaled Respiration means exchange of oxygen and carbon dioxide between the air...
Improving Biopharma Productivity through Optimal Bioreactor Operation
Generating global revenue of US billion biopharmaceuticals account for one fifth of pharmaceutical market The revenue grows at per cent annually which is double that of conventional pharmaceutical products The growing demand for therapeutic proteins and increasing focus from regulatory bodies have...
Parenteral Preparations
Challenges in Formulations
INTRODUCTION Parenteral preparations are defined as solutions suspensionsemulsions for injection or infusion powders for injection or infusion gels for injection andimplants They are sterile preparations intended to be administrated directly into the systemic circulation in human or animal body
