Pharma Articles
Articles on key issues related to the pharma industry from the heads of leading pharmaceutical companies and pharma industry experts across the globe. The pharma industry articles' section focuses on current and emerging issues in areas such as Strategic developments in the pharma industry, pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical manufacturing, biopharmaceuticals, and information technology.
Oral Formulation of Bio-pharmaceuticals
Microencapsulation systems with self-controlled macroscopic pores
Introduction There are several key factors making oral delivery systems the most attractive delivery route for pharmaceutical researchers and industry In addition to patients compliance oral delivery provides advantages such as a very large surface area for drug absorption about m elimination o...Are you Ready for EU FMD?
Urgency, consistency and planning are key
With the deadline looming for enactment of EU FMD and US DSCSA Vikash Pushpraj Senior Vice President rfxcel explains how achieving compliance is about much more than technology Companies not yet set up for serialisation will need to adopt best practices and leverage the knowhow of implementation exp...Vaccine Adjuvants
Past, Present, and Future
Introduction Next to clean water vaccines have had the most important significance in terms of prevention and treatment of diseases becoming the most successful medical invention in the past Century Vaccines have evolved significantly since the development of first successful smallpox vaccine in...Identification of Vaccine Products and Drug Substances by Fourier Transform Infrared (FTIR) Spectroscopy
Introduction Vaccine manufacturing processes involve numerous steps and can take up to months before the final product can be released for human use There are typically multiple process monitoring and product quality control tests required to cover the entire process of vaccine manufacturing In...3D Cell Culture Technique
A next generation tumor research in translational medicine
Introduction Tumor cell culture as one of the vital technique utilised in tumor cell biology for estimation of potentiality of developed formulation or newly established chemical entity or therapeutics in cancer cell killing The two dimensional monolayer cell cultures has certain limitation of be...Life-style, Environment, and Lack of Prediabetes Diagnosis Fueling Diabetic Epidemic
Introduction For the past ten years ample evidence exists to suggest that what we eat and how we live determines how our body and genes behave A rapid rise in diabetic population noticed during the past thirty years has largely been attributed to lifestyle and physical inactivity While the lifest...Multifunctional Nano-Cargo for Drug Delivery to Tumor Cells
Introduction Although multiple therapies are used in treating cancer disease amongst affected individuals it still continues to be progressing worldwide Conventional chemotherapy instead of achieving a positive outcome waiting for a longer time it rather worsens the condition as evident from case...Cancer Stem Cell (CSC) Inhibitors
Marching Towards Curing Cancer?
Cancer as a group of heterogeneous diseases very well known Unimaginable amounts of money and manhours have been spent in finding cure for this deadly disease Howeverit still remains in the top five list of diseases affecting mankind Millions of patients suffer worldwide every single day hoping to g...Enhancement of the Aqueous Solubility and Permeability of Poorly Water- Soluble Drugs
Introduction Combinatorial chemistry High Throughput Screening technique HTS and other computeraided methods have proved their usefulness for drug design and development with requisite pharmacological activity Bajaj et al To attain increased potency receptor binding is utmost important where rec...Blood-Brain Barrier and CNS Drug Delivery
Introduction The idea of Blood Brain Barrier BBB dates back to more than years ago when Paul Erlich observed that by intravenous injection of certain dyes all organs of the animal body were stained except the brain and the spinal cord The densely packed brain endothelial cells are the main part of...Nanocomposite Hybrid Metal-Organic Framework in Drug Delivery and Theranostic application
Introduction MOFs are evolving novel hybrid materials comprised of two component of inorganic and an organic fraction with diverse physicochemical characteristics MOFs have a high degree of porosity size tunability biocompatibility biodegradability and functionalisation capabilities Structurally M...Nanotherapeutic Intervention in Cancer Disease
Introduction Cancer is second most prevalent and lethal disease after cardiovascular disorder despite of advances in tumor biology research and chemotherapy The nanotechnology tremendously growing with due advances in nanomedicine and drug delivery system The mantra of nanotherapy in cancer based o...Mesoporous Silica Nanoparticles
Applications and Apprehensions
Mesoporous Silica Nanoparticles MSNs have attracted great attention over the last decade as a drug delivery system in the fields of biotechnology and Nano medicine due to their unique and adjustable physiochemical properties MSNs were first synthesised by Mobil researchers in and were called Mobil...Antimicrobial Stewardship Prioritising Quality Access to Healthcare
Antimicrobials treatments that kill or inhibit the growth of microorganisms are effective and necessary in medicine However organisms and microbes have increasingly begun to resist antimicrobial agents through evolutionary change and mutations Resistance to antimicrobials creates a difficult path fo...The European Lead Factory
A working model for collaborative public-private drug discovery
In drug discovery the search for new chemical equity to be developed into valuable preclinical and clinical candidates is very time and costintensive This is a particular difficulty for academics or small and medium enterprises SMEs who are likely to have limited resources Additionally small compani...
